Witness of a new era Moderna annouced their pre-clinical data entitled “Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia”. They showed positive results for methylmalonic acidemia/aciduria (MMA) murine models by treating with codon-optimized human methylmalonyl-CoA mutase (hMUT) mRNA. This, however is not even counted as ...

The next success in RNA-therapeutics? Yesterday, Arrakis Therapeutics announced exclusive license to RNA-targeted small molecule technology from the University of Pennsylvania. From The RNA Drug Hunter article, Arrakis had developed a compound that binds a three-way junction in an undisclosed RNA target. See David M. Chenoweth paper for more i...

Single Cell Analysis Cell press published an overview issue on the Single Cell Analysis, that combined recent review papers and reports in Single Cell area. Now I am lost in papers.

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